Often, the patient with keratoconus has seen several doctors before landing on your chair. They are anxious, wondering if this consultation will be any...
Despite the significant advancements and investments in creating more comfortable contact lenses, the number of people who wear them has not significantly increased worldwide. Researchers have attempted to understand the etiology of contact lens discomfort to develop effective management strategies. However, it is crucial to differentiate between discomfort and dry eye disease caused by contact lenses.
The etiology of VKC is multifactorial. However, the increased levels of IgE in the tear film plays a pivotal role in its occurrence. VKC is a type 1 hypersensitivity reaction with Th2 lymphocytes acting as mediators, activating basophils and eosinophils, leading to mast cell degradation and a subsequent release of histamines. The itchy sensation and conjunctival redness seen in this disease result from these reactions.
